Markus Meyer, MD
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Markus Meyer, MDEducation:Medical School Training:ResidencyFletcher Allen Health Care, Burlington, VTFellowshipFletcher Allen Health Care, Burlington, VT Specialty:Heart Failure Certifications:Internal Medicine
Cardiovascular Disease Academic Appointments:Assistant Professor of Medicine Biography:Dr. Meyer is a recent addition to our faculty. His primary clinical and research interest is heart failure. He received his training at the Albert-Ludwigs Universität Freiburg, Germany and at the Lepold-Franzens Universität Innsbruck, Austria where he completed a "magna cum laude" thesis in Biochemistry. After clinical training in Cardiology in Freiburg he and his wife moved to San Diego to work at the University of California to take advantage of genetic approaches to further investigate the roles of calcium in heart failure. Dr. Meyer completed his clinical training at the Fletcher Allen Health Care and is Board certified in Internal Medicine and Cardiology. He is recipient of several awards including an American Heart Association Scientist Development Grant, National Interest Waiver sponsored by the National Institutes of Health, Harriet P. Dustan Research Award, Frank L. Babbot Clinical Award, American College of Physicians Merck Research Award, Goedeke Young Investigator Award and was Fellow of the German Research Foundation between 1997 to 1999. Dr. Meyer's work is cited in medical textbooks and he is the inventor of several novel approaches leading to patents and patent applications. Dr. Meyer is married to Susanne Trost MD an endocrinologist. The couple and their two sons reside in Randolph , Vermont to be closer to one of their favorite past-times -- Skiing.Major Research Interests:Dr. Meyer's primary research interest is mechanisms responsible for and improved treatment of heart failure. His specific focus is to elucidate the role of cellular calcium handling in heart failure. Publications:Representative Publications from a total of 31 Meyer M, Maly K, Überall F, Hoflacher J, Grunicke H. Stimulation of K+ transport systems by Ha-ras. J Biol Chem 266:8230-8235, 1991 Hasenfuss G, Reinecke H, Studer R, Meyer M, Pieske B, Holtz J, Holubarsch C, Posival H, Just H, Drexler H. Relation between myocardial function and expression of sarcoplasmic reticulum Ca2+-ATPase in failing and nonfailing human myocardium. Circ Res 75:434-442, 1994 Pieske B, Kretschmann B, Meyer M, Holubarsch C, Posival H, Minami K, Just H, Hasenfuss G. Alterations in intracellular calcium handling associated with the inverse force frequency relation in human dilated cardiomyopathy. Circulation 92:1169-1178, 1995 Meyer M, Schillinger W, Pieske B, Holubarsch C, Heilmann K, Posival H, Kuwajiama G, Katsuhiko M, Just H, and Hasenfuss G. Alteration of sarcoplasmic proteins in failing human dilated cardiomyopathy. Circulation 92:778-784, 1995 He H, Giordano FJ, Hilal-Dandan R, Choi DJ, Rockman HA, McDonough PM, Bluhm WF, Meyer M, Sayen MR, Swanson E, Dillmann WH. Overexpression of the rat sarcoplasmic reticulum Ca2+-ATPase gene in the heart of transgenic mice accelerates calcium transients and cardiac relaxation. J Clin Invest 100:380-389, 1997 Giordano FJ, He H, McDonnough P, Meyer M, Sayen MR, Dillman WH. Adenovirus-mediated gene transfer reconstitutes depressed sarcoplasmic reticulum Ca2+-ATPase levels and shortens prolonged cardiac myocyte Ca2+ transients. Circulation 96:400-403, 1997 Meyer M, Keweloh B, Güth K, Holmes JW, Pieske B, Lehnart SE, Just H, Hasenfuss G. Frequency-dependence of myocardial energetics in failing human myocardium as quantified by a new method for the measurement of oxygen consumption in muscle strip preparations. J Mol Cell Cardiol 30:1459-1470, 1998 He H, Meyer M, Martin JL, Lou X, Lew WYW, Hilal-Dandan R, Dillmann W. The effects of mutant and antisense phospholamban on SR Ca2+-ATPase activity and myocyte contractility. Circulation 100:974-980, 1999 Bluhm WF, Kranias EG, Dillmann WH, Meyer M. Phospholamban determines frequency response and postrest potentiation of cardiac muscle. Am J Physiol, 278:H249-H255, 2000 Trost SU, Belke D, Bluhm WF, Meyer M, Swanson E, Dillmann WH. Overexpression of the sarcoplasmic reticulum Ca(2+)-ATPase improves myocardial contractility in diabetic cardiomyopathy. Diabetes, 51:1166-1171, 2002 Meyer M, Belke DD, Trost SU, Swanson E, Dieterle T, Scott B, Cary SP, Ho P, Bluhm WF, McDonough PM, Silverman GJ, Dillmann WH A recombinant antibody increases cardiac contractility by mimicking phospholamban phosphorylation. FASEB J. 2004 Aug;18(11):1312-4. Dieterle T, Meyer M, Gu Y, Belke DD, Swanson E, Ashikaga H, Iwatate M, MD, McDonough P, Hollander J, Peterson KL, Ross JJr, Dillmann WH. Gene transfer of a phospholamban-targeted antibody improves intracellular calcium handling and cardiac function in heart failure Cardiovasc Res. 2005 Sep 1;67(4):678-88 Meyer M, Dauerman HL, MD, Bell SP, LeWinter MM, Lustgarten DL. Coronary Venous Capture of Contrast During Angiography. Accepted for publication in Journal of Interventional Cardiology 2006 |
